As can be imagined, the range of geographical and climatic regions has led to a diverse variety of flora and fauna within the Annapurna region. Both Pokhara and Besishahar are below 1000 meter elevation and their climate is quite tropical. These parts of the area are heavily cultivated and the landscape, therefore, largely consists of terraced paddy fields for most of the year. The area is also famous for its winter crops of oranges, which can be purchased fresh from the trees along the trails in the foothills. As you progress higher up into the hills the natural vegetation changes from the tropical species to more temperate stands of forest trees including oak, beech and rhododendron. These finally give way to coniferous forests of pine and, ultimately, juniper just below the tree line. In the rain shadow, to the north of the mountains, the landscape is quite barren being an extension south of the Tibetan plateau. Here there are only stunted bushes and shrubs except for close to the rivers where irrigated cropping is possible.

Native animals to be seen include many birds the most obvious being the pika, blue sheep and Himalayan Tahr.